A standout home with tons of unique character on display, 111 S 43rd St is a 2,580 sqft residence offering 3 bedrooms + multiple flex spaces, 2.5 bathrooms, a patio, a second kitchen, and a fantastic location in the heart of University City. Out front, first impressions are impressive, with a 2-story stone porch accented by grand columns, dramatic windows, and a distinctive wood design feature. Inside, soaring shiplap ceilings and hardwood floors frame the bright and air living room. A towering fireplace flanked by windows anchors the space while wainscotting trims the walls. Past the spiral staircase, there's an open den and a dining area. Woodwork decorates the wall leading to the main kitchen, which is fitted with inset cabinetry, stainless steel appliances, granite counters, a tile backsplash, and a breakfast bar. At the rear is a powder room and a laundry room with access to the expansive basement and a quiet patio ideal for summer barbecues and al fresco dining. Up on the second level, a loft overlooking the living room acts as the perfect office with built-in shelving and storage. Parquet floors and more intricate millwork adorn the hall leading to a spa-like full bathroom with luxurious tile, a custom double vanity, and a glass-enclosed multi-jet shower. Continuing back, there's a pair of connecting rooms that could be transformed into a hotel-inspired primary suite with a large bedroom and a sun-soaked dressing room, gym, or study. The third level has another bonus space at the front, ideal for a media room or hobbies, two more spacious bedrooms, a full bathroom, and a second full kitchen. In addition to everything inside, this sought-after location earns a Walk Score of 96! The area is filled with top-rated restaurants, local shops, lively entertainment, and popular markets. The University of Penn and Drexel University are close, plus there's easy access to public transit, 30th St Station, Market St, and I-76. Schedule your showing today!